Current Categories of Treatment

Current osteoporosis treatments fall into 2 categories:

anabolic and antiresorptive agents1,2

Anabolic and antiresorptive osteoporosis treatment agents increase BMD through different mechanisms of action.2-5
Osteoporosis Drug Categories
Osteoporosis Drug Categories
Age-related bone loss, which accelerates at menopause, compounds fracture risk for postmenopausal patients with osteoporosis.7,8
Osteoporosis Drug Categories Warning
After an osteoporotic fracture, consider speaking to your patients about initiating treatment to reduce the risk of future fracture.


1. Camacho PM, Petak SM, Binkley N, et al. American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for the diagnosis and

treatment of postmenopausal osteoporosis—2016. Endocr Pract. 2016; (Suppl 4):1-42.

2. Baron R, Hesse E. Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives. J Clin Endocrinol Metab. 2012;97(2):311-325.

3. Girotra M, Rubin MR, Bilezikian JP. Anabolic agents for osteoporosis. What is their likely place in therapy? Treat Endocrinol. 2006;5(6):347-358.

4. Khan AW, Khan A. Anabolic agents: a new chapter in the management of osteoporosis. J Obstet Gynaecol Can. 2006;28(2):136-141.

5. Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature. 2003;423(6937):337-342.

6. Seeman E, Delmas PD. Bone quality—the material and structural basis of bone strength and fragility. N Engl J Med. 2006;354(21):2250-2261.

7. Farr JN, Khosla S. Skeletal changes through the lifespan—from growth to senescence. Nat Rev Endocrinol. 2015;11(9):513-521.

8. National Institutes of Health, National Institute on Aging. Menopause. 2013. Accessed November 9, 2016.